Chemistry

B.S. Department of Chemistry · UC Irvine · 2026-2027 Catalog

The major in Chemistry is elected by students planning careers in the chemical sciences and frequently also by those whose interests lie in other disciplines such as biology, medicine, public health, earth sciences, ecology, secondary education, business, and law. New freshman and transfer Chemistry students are strongly encouraged to take an orientation seminar, CHEM 11, where they learn about the Chemistry major requirements, the Chemistry Department, and the career options available to students after graduation.

The curriculum of the Department is designed to satisfy the diverse needs of these students and others who may have occasion to study chemistry. The year-long lecture course sequence of CHEM M2A-CHEM M2B-CHEM M2C and laboratory course sequence of CHEM M2LA-CHEM M2LB-CHEM M3LC cover the fundamentals of general and analytical chemistry, and serve as prerequisites to all study in the Department at more advanced levels. The subject matter of these courses also serve as a thorough introduction to the varied aspects of modern chemistry for students who do not wish to pursue their studies beyond the introductory level.

Completion of a one-year sequence in organic chemistry lectures, CHEM 51A-CHEM 51B-CHEM 51C, along with organic chemistry laboratory courses, is required for Chemistry majors and for students of the life sciences. These core organic chemistry courses are typically taken by students in their second year at UCI. All Chemistry students then take inorganic chemistry lecture and laboratory courses, CHEM 107 and CHEM 107L, an advanced instrumental analysis course, CHEM 152, and a three-quarter sequence of physical chemistry, CHEM 132A – CHEM 132B – CHEM 132C. Students will also take a mathematical and computing skill course, CHEM 5, in parallel with CHEM 132A, to help them improve their learning experience in the physical chemistry sequence.

To complete the Chemistry major requirements, the students take a minimum of five upper-division elective courses chosen from a broad menu, which includes graduate level courses. Certain advanced courses required of Chemistry majors may also be of interest to other majors. Many students elect to take a pre-defined set of elective courses in order to fulfill requirements for one of the concentrations and specializations, such as Chemical Biology, Chemistry Education, Environmental Chemistry, Medicinal Chemistry, Nuclear and Radiochemistry, Synthetic Chemistry, or Theoretical and Computational Chemistry and Quantum Science. For example, Chemistry majors who are interested in teaching chemistry at the secondary level often complete the optional concentration in Chemistry Education.

The undergraduate program of the Chemistry Department emphasizes close contact with research, and all Chemistry majors are encouraged to engage in research or independent study under the direction of a faculty member. Research is an integral requirement of the ACS certified degree, and it greatly increases chances for admission into graduate and professional schools. Students have an opportunity to write their research thesis as part of an upper-division writing course CHEM 180W (CHEM H181W in the Honors sequences). Information describing the procedures for arranging an undergraduate research opportunity is available on the Chemistry Department website.

Chemistry majors who plan subsequent study in medical, dental, or other professional schools should request information concerning admission requirements directly from the schools which they seek to enter. Excellent counseling about preparation for a career in the health sciences is provided by the health science advisors in the School of Biological Sciences. Those intending to pursue graduate studies in chemistry should discuss their plans with a research area advisor no later than the fall quarter of their senior year. The current advisors for each research area are listed on the Chemistry Department website.

Admission

Students may be admitted to the Chemistry major upon entering the University as freshmen, via change of major, or as transfer students from other colleges and universities. Information about change of major policies is available in the Physical Sciences Student Affairs Office and at the UCI Change of Major Criteria website. For transfer student admission, preference will be given to junior-level applicants with the highest grades overall and who have satisfactorily completed the following required courses: one year of general chemistry with laboratory and one year of approved calculus. Completion of one year of organic chemistry is strongly recommended.

Requirements

All students must meet the University Requirements. School Requirements: None.

Departmental Requirements1

CourseTitleUnits
Core Requirements
MATH 2A & MATH 2B & MATH 2DSingle-Variable Calculus Iand Single-Variable Calculus IIand Multivariable Calculus I
PHYSICS 7C & PHYSICS 7D & PHYSICS 7EClassical Physicsand Classical Physicsand Classical Physics
PHYSICS 7LC & PHYSICS 7LDClassical Physics Laboratoryand Classical Physics Laboratory
CHEM M2A & CHEM M2B & CHEM M2CMajors General Chemistry Lectureand Majors General Chemistry Lectureand Majors General Chemistry Lecture
CHEM M2LA & CHEM M2LBMajors General Chemistry Laboratoryand Majors General Chemistry Laboratory
CHEM M3LCMajors Quantitative Analytical Chemistry Laboratory
Complete the following organic chemistry sequences and accompanying labs:
CHEM 51A & CHEM 51B & CHEM 51COrganic Chemistryand Organic Chemistryand Organic Chemistry
CHEM M52LA & CHEM M52LB & CHEM M52LCMajors Organic Chemistry Laboratoryand Majors Organic Chemistry Laboratoryand Majors Organic Chemistry Laboratory
Complete:
CHEM 5Scientific Mathematical and Computing Skills
orMATH 3AIntroduction to Linear Algebra
CHEM 107 & CHEM 107LInorganic Chemistryand Inorganic Chemistry Laboratory
CHEM 152Advanced Analytical Chemistry
orCHEM 153Physical Chemistry Laboratory
CHEM 132A & CHEM 132B & CHEM 132CChemical Thermodynamics, Kinetics, and Dynamicsand Quantum Principles, Spectroscopy, and Bondingand Molecular Structure and Elementary Statistical Mechanics
Elective Requirements
Select at least five electives from the following lists, including at least two courses selected from the lecture list and at least two courses selected from the laboratory list:
Lectures:
BIO SCI 98Biochemistry
BIO SCI 99Molecular Biology
BIO SCI M114Advanced Biochemistry
BIO SCI M116Advanced Molecular Biology
BIO SCI M123Introduction to Computational Biology (same as BME 132)
CBE 110Reaction Kinetics and Reactor Design
CBE 130Separation Processes
CBE 145Chemical Process Control
CBE 161Introduction to Biochemical Engineering
CBE 181Polymer Science and Engineering
CBE 183Surface and Adhesion Science
CHEM 100Special Topics in Chemistry
CHEM 125Advanced Organic Chemistry
CHEM 127Inorganic Chemistry II
CHEM 128Introduction to Chemical Biology
CHEM 133Nuclear and Radiochemistry
CHEM 138Introduction to Computational Organic Chemistry
CHEM 141Environmental Chemistry
CHEM 145AGas-Phase Atmospheric Chemistry
CHEM 145BMulti-Phase Atmospheric Chemistry
CHEM 150Computational Chemistry
CHEM 177Medicinal Chemistry
CHEM 201Organic Reaction Mechanisms I
CHEM 202Organic Reaction Mechanisms II
CHEM 203Organic Spectroscopy
CHEM 204Organic Synthesis I
CHEM 205Organic Synthesis II *
*or any four-unit CHEM course numbered between 210-269
EARTHSS 142Atmospheric Chemistry
EARTHSS 144Marine Geochemistry and Biogeochemistry
ENGRCEE 162Introduction to Environmental Chemistry
ENGRMAE 114Fuel Cell Fundamentals and Technology
ENGRMAE 164Air Pollution and Control
MSE 141Nano-Scale Materials and Applications
MSE 164X-ray Diffraction, Electron Microscopy, and Microanalysis
PHRMSCI 170AMolecular Pharmacology I
PHRMSCI 170BMolecular Pharmacology II
PHRMSCI 171Physical Biochemistry
PHYSICS 111A & PHYSICS 111BClassical Mechanicsand Classical Mechanics
PHYSICS 112A & PHYSICS 112BElectromagnetic Theoryand Electromagnetic Theory
PUBHLTH 171Human Exposure to Environmental Contaminants
Laboratories:
BIO SCI M114LBiochemistry Laboratory
BIO SCI M116LMolecular Biology Laboratory
BIO SCI M118LExperimental Microbiology Laboratory
CBE 140AChemical Engineering Laboratory I
CBE 140BChemical Engineering Laboratory II
CHEM 128LIntroduction to Chemical Biology Laboratory Techniques
CHEM 133LNuclear and Radiochemistry Laboratory
CHEM 150LComputational Chemistry Laboratory
CHEM 153Physical Chemistry Laboratory
CHEM 156Advanced Laboratory in Chemistry and Synthesis of Materials
CHEM 160Organic Synthesis Laboratory
CHEM 177LMedicinal Chemistry Laboratory
CHEM 180Undergraduate Research 3
CHEM 197Professional Internship 4
EARTHSS 114Earth System Science Laboratory and Field Methods
orEARTHSS 115Aquatic Field Methods
  1. Courses must be taken for a letter grade.
  2. At least three of the courses used to satisfy the Elective Requirement must be courses offered by the Chemistry Department, including at least one lecture course and one laboratory course. A course applied to the Core Requirement section cannot be used for the Elective Requirement section.
  3. CHEM 180 and CHEM H180 can be counted toward this requirement no more than once.
  4. CHEM 197 must be taken for 4 units and can be counted toward this requirement no more than once.

Optional American Chemical Society Certification

CourseTitleUnits
For ACS Certification, the program must include:
A. The Chemical Biology lecture and lab courses:
CHEM 152Advanced Analytical Chemistry
CHEM 128Introduction to Chemical Biology
CHEM 128LIntroduction to Chemical Biology Laboratory Techniques
B. One course selected from the following:
CHEM 153Physical Chemistry Laboratory
CHEM 156Advanced Laboratory in Chemistry and Synthesis of Materials
CHEM 160Organic Synthesis Laboratory
CHEM 180Undergraduate Research
CHEM H180AHonors Research in Chemistry
CHEM H180BHonors Research in Chemistry
CHEM H180CHonors Research in Chemistry
C. One course or the lecture/lab pair selected from:
CHEM 125Advanced Organic Chemistry
CHEM 127Inorganic Chemistry II
CHEM 133Nuclear and Radiochemistry
CHEM 133LNuclear and Radiochemistry Laboratory
CHEM 138Introduction to Computational Organic Chemistry
CHEM 141Environmental Chemistry
CHEM 150Computational Chemistry
CHEM 150LComputational Chemistry Laboratory
CHEM 177Medicinal Chemistry
CHEM 177LMedicinal Chemistry Laboratory
CHEM 201Organic Reaction Mechanisms I
CHEM 202Organic Reaction Mechanisms II
CHEM 203Organic Spectroscopy
CHEM 204Organic Synthesis I
CHEM 205Organic Synthesis II *
*or any four-unit CHEM course numbered between 210-269
D. One course or the lecture/lab pair selected from list B or C.
E. Independent research with a written thesis submitted as part of CHEM 180W or CHEM H181W.
Optional Concentrations and Specializations in Chemistry

The core chemistry curriculum provides the students with the foundational knowledge of the traditional areas of chemistry. In addition, the students have an option to focus their education on one of the following areas of chemistry by completing the chemistry core requirements and strategically choosing their elective requirements as shown below. At least two quarters of undergraduate research (CHEM 180, CHEM H180A, CHEM H180B, CHEM H180C) with a research group chosen in consultation with the faculty advisors are strongly recommended but not required for all the concentrations and specializations listed below. The names of the faculty advisors for each concentration and specialization can be found on the Department of Chemistry website.

Only one specialization or concentration may appear on the transcript. If students simultaneously satisfy requirements for more than one specialization or concentration, they should choose which one will be appearing on their transcript.

Optional Concentration in Chemical Biology

CourseTitleUnits
BIO SCI 97Genetics
BIO SCI 98Biochemistry
BIO SCI 99Molecular Biology
CHEM 128Introduction to Chemical Biology
CHEM 128LIntroduction to Chemical Biology Laboratory Techniques

Optional Specialization in Environmental Chemistry

CourseTitleUnits
CHEM 145AGas-Phase Atmospheric Chemistry
orEARTHSS 142Atmospheric Chemistry
EARTHSS 144Marine Geochemistry and Biogeochemistry
CHEM 141Environmental Chemistry
CHEM 152Advanced Analytical Chemistry
CHEM 153Physical Chemistry Laboratory

Optional Specialization in Medicinal Chemistry

CourseTitleUnits
CHEM 128Introduction to Chemical Biology
CHEM 128LIntroduction to Chemical Biology Laboratory Techniques
CHEM 160Organic Synthesis Laboratory
CHEM 177Medicinal Chemistry
CHEM 177LMedicinal Chemistry Laboratory

Optional Specialization in Nuclear and Radiochemistry

CourseTitleUnits
CHEM 133Nuclear and Radiochemistry
CHEM 133LNuclear and Radiochemistry Laboratory
CHEM 152Advanced Analytical Chemistry
CHEM 153Physical Chemistry Laboratory
and an approved elective

Optional Specialization in Synthetic Chemistry

CourseTitleUnits
CHEM 125Advanced Organic Chemistry
CHEM 127Inorganic Chemistry II
CHEM 156Advanced Laboratory in Chemistry and Synthesis of Materials
CHEM 160Organic Synthesis Laboratory

Optional Concentration in Chemistry Education

CourseTitleUnits
CHEM 193Research Methods
EDUC 55Knowing and Learning in Mathematics and Science
PHY SCI 5California Teach 1: Introduction to Science and Mathematics Teaching
PHY SCI 105California Teach 2: Middle School Science and Mathematics Teaching
Optional Concentration in Theoretical and Computational Chemistry and Quantum Science

The concentration in Theoretical and Computational Chemistry and Quantum Science aims to provide a rigorous education for Chemistry majors with special interests in theory and computation and quantum science. Compared to the regular Chemistry major, additional courses in mathematics, physics, and computer science are required, while upper-division laboratory courses are option. Enrolling in this concentration requires approval by a faculty advisor. The advisors will be members of the Theoretical and Computational Chemistry faculty group, and will assist the students in choosing elective courses tailored to the students' interests.

CourseTitleUnits
A. Complete the following:
MATH 3AIntroduction to Linear Algebra
PHYSICS 50Introductory Mathematical Physics
CHEM 150Computational Chemistry
CHEM 150LComputational Chemistry Laboratory
Select at least nine courses from the following or the Chemistry major electives:
B. Select at least one from the following:
PHYSICS 111AClassical Mechanics
PHYSICS 112AElectromagnetic Theory
PHYSICS 111BClassical Mechanics
PHYSICS 112BElectromagnetic Theory
PHYSICS 113AQuantum Mechanics
PHYSICS 113BQuantum Mechanics
PHYSICS 113CQuantum Mechanics
PHYSICS 115AStatistical Physics
PHYSICS 125AMathematical Physics
PHYSICS 125BMathematical Physics
C. Select at least one from the following:
MATH 105A & MATH 105LANumerical Analysis Iand Numerical Analysis Laboratory
MATH 105B & MATH 105LBNumerical Analysis IIand Numerical Analysis Laboratory
STATS 7Basic Statistics
STATS 110Statistical Methods for Data Analysis I
STATS 111Statistical Methods for Data Analysis II
STATS 112Statistical Methods for Data Analysis III
D. Select at least one of the following:
EECS 12Introduction to Programming
EECS 20Computer Systems and C Programming
EECS 22Advanced C Programming
EECS 22LSoftware Engineering Project in C Language
Optional Courses - The following courses are required for the regular Chemistry major, but optional for the Concentration in Theoretical and Computational Chemistry:
CHEM 5Scientific Mathematical and Computing Skills
CHEM 107LInorganic Chemistry Laboratory
CHEM 152Advanced Analytical Chemistry
All electives listed under the Chemistry major.
Secondary Teaching Certification Option

With additional course work and field experience offered through the UCI Cal Teach program, students who complete the concentration in Chemistry Education can also earn a California Preliminary Single Subject Teaching Credential. Completing the bachelor’s degree, concentration, and teacher certification in four years is possible with careful, early planning. Additional courses required for teacher certification are:

CourseTitleUnits
EDUC 109Reading and Writing in Mathematics and Science
EDUC 143AW & EDUC 143BWClassroom Interactions Iand Classroom Interactions II
EDUC 148Complex Pedagogical Design
EDUC 158Student Teaching Mathematics and Science in Middle/High School (two quarters)
LPS 60The Making of Modern Science

Successful completion of EDUC 143AW-EDUC 143BW and EDUC 148 will be accepted in lieu of three electives (from the above Elective Requirements list) for students pursuing the concentration in Chemistry Education. To complete the remaining electives, students may choose any combination from the approved list of lectures or laboratories, e.g. two laboratories, or two lectures, or one laboratory and one lecture. For additional information about teacher certification requirements and enrollment procedures, see Preparation for Teaching Science and Mathematics. Interested students are strongly encouraged to contact the Cal Teach Resource and Advising Center or the Physical Sciences Student Affairs Office.

Sample Programs

Sample Program — Chemistry Majors1

Items in parentheses are recommended choices or alternatives.

Freshman

Fall Winter Spring
CHEM M2A& CHEM M2LA CHEM M2B& CHEM M2LB CHEM M2C
MATH 2A MATH 2B MATH 2D
Lower-division Writing Lower-division Writing CHEM M3LC
CHEM 11

Sophomore

Fall Winter Spring
CHEM 51A& CHEM M52LA CHEM 51B& CHEM M52LB CHEM 51C& CHEM M52LC
CHEM 5 General Education PHYSICS 7E
PHYSICS 7C& PHYSICS 7LC PHYSICS 7D& PHYSICS 7LD General Education

Junior

Fall Winter Spring
CHEM 132A CHEM 132B CHEM 132C
CHEM 107 Chemistry Elective CHEM 107L
Chemistry Elective General Education Elective
General Education General Education General Education

Senior

Fall Winter Spring
Elective/Research CHEM 152 Elective/Research
Upper-division Writing Elective/Research Chemistry Elective
Chemistry Elective General Education General Education
General Education General Education
Sample Program - Concentration in Theoretical and Computational Chemistry

Items in parentheses are recommended choices or alternatives.

Freshman

Fall Winter Spring
CHEM M2A& CHEM M2LA CHEM M2B& CHEM M2LB CHEM M3LC
MATH 2A MATH 2B MATH 2D
Lower-Division Writing Lower-Division Writing General Education

Sophomore

Fall Winter Spring
CHEM 51A& CHEM M52LA CHEM 51B& CHEM M52LB CHEM 51C& CHEM M52LC
PHYSICS 7C& PHYSICS 7LC PHYSICS 7D& PHYSICS 7LD PHYSICS 7E
MATH 3A

Junior

Fall Winter Spring
CHEM 132A CHEM 132B CHEM 132C
CHEM 107 PHYSICS 112A PHYSICS 113A
PHYSICS 111A General Education EECS 20
EECS 12 General Education General Education
PHYSICS 50

Senior

Fall Winter Spring
CHEM 150 CHEM 150L Elective/Research
MATH 105A& MATH 105LA EECS 22L (MATH 105B - MATH 105LB) General Education
EECS 22 (STATS 7) General Education General Education
Upper-Division Writing General Education General Education
Sample program for transfer students entering at the Junior level

Junior

Fall Winter Spring
CHEM 132A CHEM 132B CHEM 132C
CHEM 107 STATS 7 PHYSICS 50
MATH 105A& MATH 105LA General Education EECS 20
EECS 12 General Education General Education

Senior

Fall Winter Spring
CHEM 150 CHEM 150L PHYSICS 113A
PHYSICS 111A PHYSICS 112A EECS 22L
General Education General Education General Education
Upper-Division Writing General Education General Education
Sample Program — Concentration in Chemistry Education (with Secondary Teaching Certification option)

Items in parentheses are recommended choices or alternatives.

Freshman

Fall Winter Spring
CHEM M2A& CHEM M2LA CHEM M2B& CHEM M2LB CHEM M3LC
MATH 2A MATH 2B MATH 2D
PHY SCI 5 General Education General Education

Sophomore

Fall Winter Spring
CHEM 51A& CHEM M52LA CHEM 51B& CHEM M52LB CHEM 51C& CHEM M52LC
CHEM 5 PHYSICS 7C& PHYSICS 7LC PHYSICS 7D& PHYSICS 7LD
PHY SCI 105 CHEM 193 LPS 60
(PHYSICS 2) General Education

Junior

Fall Winter Spring
CHEM 132A CHEM 132B CHEM 132C
CHEM 107 CHEM 152 CHEM 107L
EDUC 55 EDUC 143AW EDUC 148
PHYSICS 7E Chemistry Elective

Senior

Fall Winter Spring
Chemistry Elective General Education General Education
EDUC 143BW EDUC 109 EDUC 158
General Education EDUC 158

Honors

The Honors Program in Chemistry is a research-based program offered to selected Chemistry majors during their final year. Applicants to the program must have completed their junior year with a grade point average of at least 3.3 overall and in their Chemistry courses. They must also have demonstrated the potential of carrying out research of honors quality, as judged by the Chemistry faculty member who will supervise their research. Students in this program enroll in Honors Research in Chemistry (CHEM H180A-CHEM H180B-CHEM H180C) throughout their senior year and submit a formal thesis late in the spring quarter. They also enroll in the Honors Seminar in Chemistry (CHEM H181W), in which they receive instruction in scientific writing and present a formal research seminar. Successful completion of CHEM H181W satisfies the UCI upper-division writing requirement. NOTE: Students enrolled in the Honors Research in Chemistry (CHEM H180A-CHEM H180B-CHEM H180C) do not enroll in CHEM 180 (Undergraduate Research).

Students who complete these requirements, whose grade point average remains above the 3.3 standard, and whose research is judged to be of honors quality will graduate with Departmental Honors in Chemistry.

Additional information is available from the Chemistry Undergraduate Program Office.

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